by Richard Lang | May 24, 2021 | Scientific Publication
Myopia has become a major public health concern, particularly across much of Asia. It has been shown in multiple studies that outdoor activity has a protective effect on myopia. Recent reports have shown that short-wavelength visible violet light is the component of...
by Richard Lang | Sep 2, 2020 | Scientific Publication
Violet-light suppression of thermogenesis by Opsin 5 Here we describe a light-sensing pathway in which POA neurons that express Opn5 regulate thermogenesis in brown adipose tissue (BAT). We show that Opn5 is expressed in glutamatergic warm-sensing POA neurons that...
by kagnes81 | Jan 21, 2020 | Scientific Publication
Adaptive Thermogenesis in Mice Is Enhanced by Opsin 3 Here we describe a light response pathway in mice that employs encephalopsin (OPN3, a 480 nm, blue-light-responsive opsin) to regulate the function of adipocytes. Germline null and adipocyte-specific conditional...
by Richard Lang | Oct 21, 2019 | Scientific Publication
Neuropsin (OPN5) Mediates Local Light-Dependent Induction of Circadian Clock Genes and Circadian Photoentrainment in Exposed Murine Skin Here, we assess the function of a population of melanocyte precursor cells in hair and vibrissal follicles that express the...
by Richard Lang | Apr 21, 2019 | Scientific Publication
An opsin 5-dopamine pathway mediates light-dependent vascular development in the eye During mouse postnatal eye development, the embryonic hyaloid vascular network regresses from the vitreous as an adaption for high-acuity vision. This process occurs with precisely...