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Research Overview

Connecting basic science discoveries on ligh sensing pathways to healthcare

Research Publications

Leading revolutionary scientific research for a brighter future

Clinical studies

Innovation that leads to quality care

Basic Science

We use  basic science findings to inform clinical research

Richard Lang Lab

We investigate how intra- and extraocular light sensing pathways regulate development, homeostasis and disease.

Diego Fernandez Lab

Laboratory of sensory and circadian integration

NICU SPECTRAL LIGHTING

Spectral lighting system for heath innovations

SkyView Lamp

Highlighting innovative technology created from biological discoveries 

Events & Lectures

Blog Post

Comic Book

A Discovery that can Prevent the need for Eyeglasses

by Richard Lang | May 24, 2021 | Scientific Publication

Myopia has become a major public health concern, particularly across much of Asia. It has been shown in multiple studies that outdoor activity has a protective effect on myopia. Recent reports have shown that short-wavelength visible violet light is the component of...

Violet-light suppression of thermogenesis by Opsin 5

by Richard Lang | Sep 2, 2020 | Scientific Publication

Violet-light suppression of thermogenesis by Opsin 5 Here we describe a light-sensing pathway in which POA neurons that express Opn5 regulate thermogenesis in brown adipose tissue (BAT). We show that Opn5 is expressed in glutamatergic warm-sensing POA neurons that...

Adaptive Thermogenesis in Mice Is Enhanced by Opsin 3

by kagnes81 | Jan 21, 2020 | Scientific Publication

Adaptive Thermogenesis in Mice Is Enhanced by Opsin 3  Here we describe a light response pathway in mice that employs encephalopsin (OPN3, a 480 nm, blue-light-responsive opsin) to regulate the function of adipocytes. Germline null and adipocyte-specific conditional...

Neuropsin (OPN5) Mediates Local Light-Dependent Induction of Circadian Clock Genes and Circadian Photoentrainment in Exposed Murine Skin

by Richard Lang | Oct 21, 2019 | Scientific Publication

Neuropsin (OPN5) Mediates Local Light-Dependent Induction of Circadian Clock Genes and Circadian Photoentrainment in Exposed Murine Skin  Here, we assess the function of a population of melanocyte precursor cells in hair and vibrissal follicles that express the...

An opsin 5-dopamine pathway mediates light-dependent vascular development in the eye

by Richard Lang | Apr 21, 2019 | Scientific Publication

An opsin 5-dopamine pathway mediates light-dependent vascular development in the eye During mouse postnatal eye development, the embryonic hyaloid vascular network regresses from the vitreous as an adaption for high-acuity vision. This process occurs with precisely...

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